Administration of anticonvulsive rescue medication in children-discrepancies between parents' self-reports and limited practical performance

作者：Kaune Almuth; Schumacher Pia Madeleine; Hoppe Sabine Christine; Syrbe Steffen; Bernhard Matthias Karl; Frontini Roberto; Merkenschlager Andreas; Kiess Wieland; Neininger Martina Patrizia; Bertsche Astrid; Bertsche Thilo^*

来源：European Journal of Pediatrics, 2016, 175(9): 1139-1146.

DOI：10.1007/s00431-016-2750-6

• Handling errors
• Anticonvulsants
• Rescue medication

Quality of parents' performance in administering anticonvulsive rescue medication to their children suffering from seizures is unknown. After obtaining ethical approval, we used a questionnaire to ask parents of children with seizures, who had been prescribed rescue medications, about their experience in administering those. To assess the frequency of actually committed drug-handling errors, we let them administer rescue medications to dummy dolls. An expert panel rated the clinical risk of handling errors from "1" (lowest) to "6" (highest). Eighty-one parents completed the study. In the questionnaire, 85 % (100 %) of parents that already conducted rectal (buccal) administration reported that they had never experienced problems. The number of rectal administrations with at least one handling error (97 %, 58/60) was higher than in buccal administration (58 %; 14/24; p < 0.001). According to logistic regressions, previous use of rescue medication was not a predictor of the number of committed errors per process (n. s.). All errors were rated with a high clinical risk (class 4-6).
Conclusion: By observing parents' administration of rescue medication to dummy dolls, we found a high frequency of clinically relevant drug-handling errors. Most parents, however, self-reported to have never experienced problems while administering rescue medications to their children.

• 出版日期2016-9