A family of hydrogels based on ureido-linked aminopolyol-derived amphiphiles and bolaamphiphiles: Synthesis, gelation under thermal and sonochemical stimuli, and mesomorphic characterization

作者：Avalos Martin; Babiano Reyes; Cintas Pedro^*; Gomez Carretero Antonio; Jimenez Jose L; Lozano Marina; Ortiz Angel L; Palacios Juan C; Pinazo Aurora

来源：Chemistry - A European Journal, 2008, 14(18): 5656-5669.

DOI：10.1002/chem.200701897

• amino sugars
• amphliphiles
• gels
• liquid crystals
• self-assembly

This article describes the systematic preparation of a novel family of carbohydrate amphiphiles and bolaamphiphiles in which hydrophilic and hydrophobic units are connected via a ureido or bis(ureido) moiety. The sugar core is derived from aminopolyols such as D-glucamine (1), N-methyl-D-glucamine (2), or the sugar-like species tris(hydroxymethyl)aminomethane (3). The O-unprotected derivatives behave as self-organizing nonionic surfactants with good water gelation ability, which can be induced under thermal or ultrasound-driven stimuli. In addition, some derivatives of 1 and 2, and rarely 3 also formed lyotropic liquid crystals with lamellar or hexagonal structures that exhibit low-temperature transitions.

• 出版日期2008