Dynamic development of the pancreas from birth to adulthood

作者:Bonner Weir Susan*; Aguayo Mazzucato Cristina; Weir Gordon C
来源:Upsala Journal of Medical Sciences, 2016, 121(2): 155-158.
DOI:10.3109/03009734.2016.1154906

摘要

After birth the endocrine pancreas continues its development, a complex process that involves both the maturation of islet cells and a marked expansion of their numbers. New beta cells are formed both by duplication of pre-existing cells and by new differentiation (neogenesis) across the first postnatal weeks, with the result of beta cells of different stages of maturation even after weaning. Improving our understanding of this period of beta cell expansion could provide valuable therapeutic insights.

  • 出版日期2016-5