A novel class of metal-directed supramolecular DNA-delivery systems

作者:Cruz Campa Itzia; Arzola Alejandro; Santiago Lynn; Parsons Jason G; Varela Ramirez Armando; Aguilera Renato J; Noveron Juan C*
来源:Chemical Communications, 2007, (28): 2944-2946.
DOI:10.1039/b703201c

摘要

The bis-complexes [Cu(L-dt)(2)](OTf)(2) (1) and [Cu(L-ot)(2)](OTf)(2) (2), where L-dt = 1-dodecyl-1,4,7-triazacyclononane, L-ot = 1-octadecyl-1,4,7-triazacyclononane and OTf = trifluoromethanesulfonate, formed a novel class of metallo-liposomes in water that transfect pEGFP-N1 plasmids into HEK 293-T cells at 38% and 4% efficiency, respectively.

  • 出版日期2007