A First-Generation Haplotype Map of Maize

作者:Gore Michael A; Chia Jer Ming; Elshire Robert J; Sun Qi; Ersoz Elhan S; Hurwitz Bonnie L; Peiffer Jason A; McMullen Michael D; Grills George S; Ross Ibarra Jeffrey; Ware Doreen H*; Buckler Edward S
来源:Science, 2009, 326(5956): 1115-1117.
DOI:10.1126/science.1177837

摘要

Maize is an important crop species of high genetic diversity. We identified and genotyped several million sequence polymorphisms among 27 diverse maize inbred lines and discovered that the genome was characterized by highly divergent haplotypes and showed 10- to 30-fold variation in recombination rates. Most chromosomes have pericentromeric regions with highly suppressed recombination that appear to have influenced the effectiveness of selection during maize inbred development and may be a major component of heterosis. We found hundreds of selective sweeps and highly differentiated regions that probably contain loci that are key to geographic adaptation. This survey of genetic diversity provides a foundation for uniting breeding efforts across the world and for dissecting complex traits through genome-wide association studies.

  • 出版日期2009-11-20

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