Diffusion-weighted whole-body imaging with background body signal suppression/T2 image fusion and positron emission tomography/computed tomography of upper gastrointestinal cancers

作者：Tomizawa Minoru; Shinozaki Fuminobu; Uchida Yoshitaka; Uchiyama Katsuhiro; Fugo Kazunori; Sunaoshi Takafumi; Ozaki Aika; Sugiyama Eriko; Baba Akira; Fukamizu Yoshiya; Kagayama Satoshi; Hasegawa Rumiko; Shirai Yoshinori; Oshima Yuji; Koike Naoto; Toshimitsu Yasuko; Motoyoshi Yasufumi; Sugiyama Takao; Yamamoto Shigenori; Kishimoto Takashi; Ishige Naoki

来源：Abdominal Imaging, 2015, 40(8): 3012-3019.

DOI：10.1007/s00261-015-0545-2

• Gastric cancer
• Gastrointestinal stromal tumor
• Duodenal cancer

Diffusion-weighted whole-body imaging with background body signal suppression/T2 image fusion (DWIBS/T2) strongly contrasts cancerous tissue against background healthy tissues. Positron emission tomography/computed tomography (PET/CT) applies the uptake of 18-fluorodeoxyglucose in the diagnosis of cancer. Our aim was to compare DWIBS/T2 and PET/CT in patients with upper gastrointestinal cancers.
Patient records, including imaging results from July 2012 to March 2015, were analyzed retrospectively. Four men (age, 72.5 +/- A 5.3 years) and ten women (age, 71.6 +/- A 4.0 years) were enrolled in this study. The numbers of patients with esophageal cancer, gastric cancer, gastrointestinal stromal tumor, and duodenal cancer were one, eight, three, and two, respectively.
Six out of eight patients with gastric cancer had positive results on both DWIBS/T2 and PET/CT. The diameter and depth of invasion of gastric cancer was larger in patients with positive DWIBS/T2 and PET/CT findings than those with negative findings. These results suggested that patients with gastric cancer with larger pixel numbers might tend to show positive results with DWIBS/T2.
DWIBS/T2 and PET/CT have similar sensitivity for the diagnosis of upper gastrointestinal cancer. The diameter and depth of invasion affected the detectability of gastric cancer.

• 出版日期2015-10