Schizophrenia impairs phonological speech production: A preliminary report

作者：Birkett Paul^*; Clegg Judy; Bhaker Rajinder; Lee Kwang Hyuk; Mysore Ashok; Parks Randolph; Woodruff Peter

来源：Cognitive Neuropsychiatry, 2011, 16(1): 40-49.

DOI：10.1080/13546801003787459

• Phonological
• Schizophrenia
• Schizophrenia syndromes
• Speech-production
• Tongue-twister

Introduction. Schizophrenia causes clinically conspicuous impairment of syntax and semantics as part of the disorganisation syndrome; however, little is known regarding its effect on the phonological stage of speech, where word meanings are resolved into speech imagery.
Methods. We used a "tongue-twister" task to probe phonological speech production and its clinical associations in six schizophrenia patients and 16 controls.
Results. Errors induced by phonological similarity were more common in the patients (p = .003), were positively associated with psychomotor poverty symptoms (p = .02) and negatively associated with reality distortion symptoms (p = .03).
Conclusions. Our findings suggest that phonological speech production is markedly disrupted by schizophrenia. Further, this phonological abnormality is distinct from disorganisation syndrome.

• 出版日期2011