Microwave-Assisted Reaction of 2,3-Dichloronaphthoquinone with Aminopyridines

作者:Tapia Ricardo A*; Cantuarias Lorena; Cuellar Mauricio; Villena Joan
来源:Journal of the Brazilian Chemical Society, 2009, 20(5): 999-1002.
DOI:10.1590/s0103-50532009000500027

摘要

The synthesis of pyridylaminonaphthoquinones by microwave-assisted reaction of 2,3-dichloro1,4-naphthoquinone with aminopyridines is described. The use of microwave irradiation diminished the reaction times and improved the yields substantially in all these reactions. The compounds were tested for their cytotoxic activities against MCF-7 breast cancer cell line.

  • 出版日期2009