Attacking the Supply Lines: HIV-1 Restricts Alanine Uptake to Prevent T Cell Activation

作者：Sugden Scott; Cohen Eric A^*

来源：Cell Host & Microbe, 2015, 18(5): 514-517.

DOI：10.1016/j.chom.2015.10.017

HIV commonly escapes host antiviral immunity by downregulating cell-surface immunoreceptors. In a recent issue of Cell Host & Microbe, Matheson et al. (2015) systematically examined how HIV-1 infection remodels the T cell surface and identified serine carriers SERINC3/5 and alanine transporter SNAT1 as targets of HIV-1 Nef and Vpu, respectively.

• 出版日期2015-11-11