Altered metabolism in cancer

作者:Locasale Jason W*; Cantley Lewis C
来源:BMC Biology, 2010, 8: 88.
DOI:10.1186/1741-7007-8-88

摘要

Cancer cells have different metabolic requirements from their normal counterparts. Understanding the consequences of this differential metabolism requires a detailed understanding of glucose metabolism and its relation to energy production in cancer cells. A recent study in BMC Systems Biology by Vasquez et al. developed a mathematical model to assess some features of this altered metabolism. Here, we take a broader look at the regulation of energy metabolism in cancer cells, considering their anabolic as well as catabolic needs.

  • 出版日期2010-6-25