Undifferentiated carcinoma of the pancreas with osteoclast-like giant cells

作者：Hur Young Hoe; Kim Ho Hyun; Seoung Jin Shick; Seo Kyoung Won; Kim Jin Woong; Jeong Yong Yeon; Lee Jae Hyuk; Koh Yang Seok; Kim Jung Chul; Kim Hyun Jong; Cho Chol Kyoon^*

来源：Journal of the Korean Surgical Society, 2011, 81(2): 146-150.

DOI：10.4174/jkss.2011.81.2.146

• Osteoclast-like giant cells
• Undifferentiated carcinoma
• Pancreas

Undifferentiated carcinoma with osteoclast-like giant cells is a rare neoplasm of the exocrine pancreas. Some similar cases have been reported, but the histogenesis of these tumors varies and is controversial. We report here on a case of undifferentiated carcinoma of the pancreas with osteoclast-like giant cells. A 77-year old woman presented with abdominal pain and anorexia. Abdominal computed tomography and magnetic resonance imaging showed an approximately 10 x 5 cm highly attenuated mass arising from the tail of the pancreas and invading the spleen and adjacent bowel loop. The initial impression was a malignant endocrine tumor or solid-pseudopapillary tumor of the pancreas. The patient underwent a distal pancreatectomy with splenectomy and left hemicolectomy. The histopathology and immunohistochemistry helped make the diagnosis that of an undifferentiated carcinoma with osteoclast-like giant cells of the pancreas.

• 出版日期2011-8