Asymmetric hydrosilylation of prochiral ketones catalyzed by nanocrystalline copper(II) oxide

作者：Kantam M Lakshmi^*; Laha Soumi; Yadav Jagjit; Likhar Pravin R; Sreedhar B; Choudary B M

来源：Advanced Synthesis & Catalysis, 2007, 349(10): 1797-1802.

DOI：10.1002/adsc.200600481

• asymmetric hydrosilylation
• heterogeneous catalysis
• nanocrystalline copper(II) oxide
• reduction
• secondary alcohols

Asymmetric hydrosilylation of aryl alkyl ketones to afford chiral secondary alcohols with good yields and excellent enantioselectivity is realized by using nanocrystalline copper(II) oxide and BINAP in the presence of organosilanes as the stoichiometric reducing agents.

• 出版日期2007-7