Non-enzymatic glucose detection based on phenylboronic acid modified optical fibers

作者：Sun, Xiaolan^*; Li, Nana; Zhou, Bin; Zhao, Wei; Liu, Liyuan; Huang, Chao; Ma, Longfei; Kost, Alan R.

来源：Optics Communications, 2018, 416: 32-35.

DOI：10.1016/j.optcom.2018.01.064

• Glucose sensor
• Evanescent wave
• Tapered optical fiber
• Phenylboronic acid (PBA)

A non-enzymatic, sensitive glucose sensor was fabricated based on an evanescent wave absorbing optical fiber probe. The optical fiber sensor was functionalized by fixing a poly (phenylboronic acid) (polyPBA) film onto the conical region of the single mode fiber. The reflected light intensity of the polyPBA-functionalized fiber sensor increased proportionally with glucose concentration in the range of 0-60 mM, and the sensor showed good reproducibility and stability. The developed sensor possessed a high sensitivity of 0.1787%/mM and good linearity. The measurement of glucose concentration in human serum was also demonstrated.

• 出版日期2018-6-1
• 单位上海大学