Natural selenium particles from Staphylococcus carnosus: Hazards or particles with particular promise?

作者:Estevam Ethiene Castellucci; Griffin Sharoon; Nasim Muhammad Jawad; Denezhkin Polina; Schneider Ramona; Lilischkis Rainer; Dominguez Alvarez Enrique; Witek Karolina; Latacz Gniewomir; Keck Cornelia; Schaefer Karl Herbert; Kie Kononowicz Katarzyna; Handzlik Jadwiga; Jacob Claus*
来源:Journal of Hazardous Materials, 2017, 324: 22-30.
DOI:10.1016/j.jhazmat.2016.02.001

摘要

Various bacteria, including diverse Staphylococci, reduce selenite to yield red selenium particles with diameters in the high nanometer to low micrometer range. Formation and accumulation of such particles in bacteria often results in cell death, triggered by a loss of thiols and formation of disruptive deposits inside the cell. Hence certain pathogenic bacteria are rather sensitive to the presence of selenite, whilst other organism, such as small nematodes, do not employ this kind of nanotechnology, yet become affected by micromolar concentrations of such naturally generated materials. Selenium particles extracted from cultures of Staphylococcus carnosus and apparently stabilized by their natural protein coating, for instance, show considerable activity against the nematode Steinernema feltiae, Escherichia coli and Saccaromyces cerevisiae. Such natural nano- and micro-particles are also more active than mechanically generated selenium particles and may be applied as antimicrobial materials in Medicine and Agriculture.

  • 出版日期2017-2-15