Abnormal Structural Correlates of Response Perseveration in Individuals With Psychopathy

作者:Yang Yaling*; Raine Adrian; Colletti Patrick; Toga Arthur W; Narr Katherine L
来源:Journal of Neuropsychiatry and Clinical Neurosciences, 2011, 23(1): 107-110.
DOI:10.1176/appi.neuropsych.23.1.107

摘要

Structural deficits in the frontotemporal network have been shown in individuals with psychopathy and are posited to contribute to neuropsychological impairments such as response perseveration. However, no study to date has examined structural correlates of response perseveration in individuals with psychopathy. In this structural MRI study, the authors found higher correlations between increased response perseveration and reduced cortical thickness in the orbitofrontal and anterior temporal regions in individuals with psychopathy than in healthy-comparison subjects. The findings provide preliminary evidence suggesting potential contributions of frontotemporal structural deficits in neurocognitive impairment with perseveration in individuals with psychopathy. (The Journal of Neuropsychiatry and Clinical Neurosciences 2011; 23:107-110)

  • 出版日期2011