Apical polarization and lumenogenesis: The apicosome sheds new light

作者:Romero Morales Alejandra I; Ortolano Natalya A; Gama Vivian*
来源:The Journal of Cell Biology, 2017, 216(12): 3891-3893.
DOI:10.1083/jcb.201710028

摘要

Establishment of apico-basal polarity is critical for the lumenal epiblast-like morphogenesis of human pluripotent stem cells (hPSCs). In this issue, Taniguchi et al. (2017. J Cell Biol.https://doi.org/10.1083.jcb201704085) describe a structure called the apicosome, generated in single hPSCs, that allows them to self-organize and form the lumenal epiblast-like stage.

  • 出版日期2017-12

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