ESCHERICHIA-COLI INTEGRATION HOST FACTOR STABILIZES BACTERIOPHAGE MU-REPRESSOR INTERACTIONS WITH OPERATOR DNA INVITRO

作者：ALAZARD R^*; BETERMIER M; CHANDLER M

来源：Molecular Microbiology, 1992, 6(12): 1707-1714.

DOI：10.1111/j.1365-2958.1992.tb00895.x

Using gel retardation and DNase I protection techniques, we have demonstrated that the Escherichia coli integration host factor (IHF) stabilizes the interaction between Mu repressor and its cognate operator-binding sites in vitro. These results are discussed in terms of a model in which IHF may commit the phage to the lytic or lysogenic pathway depending on the occupancy of the operator sites by the repressor.

• 出版日期1992-6