Direct identification of prohibited substances in cosmetics and foodstuffs using ambient ionization on a miniature mass spectrometry system

作者：Ma Qiang; Bai Hua; Li Wentao; Wang Chao; Li Xinshi; Cooks R Graham; Ouyang Zheng^*

来源：Analytica Chimica Acta, 2016, 912: 65-73.

DOI：10.1016/j.aca.2016.01.031

• Ambient ionization
• Slug-flow microextraction
• Paper spray
• Extraction spray
• Miniature ion trap mass spectrometer
• Cosmetics
• Foodstuffs
• Steroids
• Sudan Red
• Parabens
• Plasticizer

Significantly simplified work flows were developed for rapid analysis of various types of cosmetic and foodstuff samples by employing a miniature mass spectrometry system and ambient ionization methods. A desktop Mini 12 ion trap mass spectrometer was coupled with paper spray ionization, extraction spray ionization and slug-flow microextraction for direct analysis of Sudan Reds, parabens, antibiotics, steroids, bisphenol and plasticizer from raw samples with complex matrices. Limits of detection as low as 5 mg/kg were obtained for target analytes. On-line derivatization was also implemented for analysis of steroid in cosmetics. The developed methods provide potential analytical possibility for outside-the-lab screening of cosmetics and foodstuff products for the presence of illegal substances.

• 出版日期2016-3-17
• 单位中国检验检疫科学研究院