Nortriterpenoids from the roots of Paeonia emodi

作者：Tantry Mudasir A^*; Dar Javid A; Khuroo Mohammad A; Shawl Abdul S

来源：Phytochemistry Letters, 2012, 5(2): 253-257.

DOI：10.1016/j.phytol.2012.01.006

• Paeonia emodi
• Nortriterpenoids
• Cytotoxic activity

Chemical investigation of chloroform-ethyl acetate extract from the roots of Paeonia emodi yielded four hitherto unknown noroleanane triterpenoids (1-4) together with four known compounds (5-8). Their structures were established by analysis of spectroscopic data. Compounds 1-8 were evaluated for cytotoxic activities against human cancer cell lines A549, HL-60, HCT116 and ZR-75-30. Compounds 1, 2, 3, 6 and 7 showed modest cytotoxicity against HL-60, HCT116 and ZR-75-30.

• 出版日期2012-6