Ambroxol-Induced Focal Epileptic Seizure

作者:Lapenta Leonardo; Morano Alessandra; Fattouch Jinane; Casciato Sara; Fanella Martina; Giallonardo Anna Teresa; Di Bonaventura Carlo*
来源:Clinical Neuropharmacology, 2014, 37(3): 84-87.
DOI:10.1097/WNF.0000000000000031

摘要

It is well known that in epileptic patients some compounds and different drugs used for the treatment of comorbidities can facilitate or provoke seizures, this evidence regarding a wide spectrum of pharmacological categories. The potential facilitating factors usually include direct toxic effects or pharmacological interactions of either active ingredients or excipients. We report the case of a patient with drug-resistant epilepsy who experienced focal epileptic seizures, easily and constantly reproducible, after each administration of a cough syrup. This is, to our knowledge, the first electroencephalogram-documented case of focal epileptic seizures induced by cough syrup containing ambroxol as active ingredient.

  • 出版日期2014-6