Acute fibrinous and organizing pneumonia as initial presentation of primary Sjogren's syndrome: a case report and literature review

作者：Wang Yukai; Zhao Shucan; Du Guangzhou; Ma Songkun; Lin Qisheng; Lin Jianqun; Zheng Kedi; Zhang Guohong; Matucci Cerinic Marco

来源：Clinical Rheumatology, 2018, 37(7): 2001-2005.

DOI：10.1007/s10067-018-4128-9

• Acute fibrinous and organizing pneumonia
• CT patterns
• Histopathological pattern
• Primary Sjogren's syndrome

Acute fibrinous and organizing pneumonia (AFOP) is a new histopathological pattern of acute lung injury first described by Beasley et al. in 2002. Hallmarks of pathological findings are characterized by the presence of intra-alveolar fibrin in the form of fibrin "balls" within the alveolar spaces and organizing pneumonia with a patchy distribution. Patients with AFOP may have an acute or subacute clinical presentation. Although the pathogenesis of AFOP is not fully elucidated, it may be associated with autoimmune diseases. Reported herein is a patient diagnosed of acute AFOP associated with primary Sjogren's syndrome. The patient's condition promptly improved after treatment with corticosteroid.

• 出版日期2018-7
• 单位汕头市中心医院; 汕头大学