Major Limitations of Randomized Clinical Trials Involving Coronary Artery Bifurcation Interventions: Time for Redesigning Clinical Trials by Involving Only True Bifurcation Lesions and Using Appropriate Bifurcation Classification

作者：Movahed Mohammad Reza^*

来源：Journal of Interventional Cardiology, 2011, 24(4): 295-301.

DOI：10.1111/j.1540-8183.2011.00631.x

Coronary bifurcation lesion intervention is technically challenging with higher complication rates. Many coronary interventional trials have been conducted involving coronary bifurcation lesions in order to compare one-stent with two-stent techniques. However, these trials have major limitation by enrolling all bifurcation lesions, including low-risk lesions so-called not true bifurcation lesions. This manuscript discusses the importance of appropriate designing of clinical trials for evaluation of complex techniques in coronary bifurcation lesions. (J Interven Cardiol 2011;24:295-301)

• 出版日期2011-8