Determination of Descriptors for Plasticizers by Chromatography and Liquid-Liquid Partition

作者：Karunasekara Thushara; Atapattu Sanka N; Poole Colin F^*

来源：Chromatographia, 2012, 75(19-20): 1135-1146.

DOI：10.1007/s10337-012-2288-3

• Descriptors
• Liquid-liquid partition
• Gas chromatography
• Reversed-phase liquid chromatography
• Solvation parameter model
• Plasticizers
• Phthalate esters

Retention factors on a minimum of eight stationary phases at various temperatures by gas-liquid chromatography and in acetonitrile-water and methanol-water mobile phases by reversed-phase liquid chromatography on a Synergi Polar-RP column were combined with further values taken from the literature and liquid-liquid partition coefficients for up to eight totally organic biphasic systems to estimate descriptors for 24 esters (phthalate, oleate, stearate, arbietate, adipate, succinate, sebacate, and diethylmalonate) widely used as plasticizers and solvents in industry. The descriptors facilitated the estimation of several properties of environmental interest (octanol-water, air-octanol, and air-water partition coefficients, and soil-water distribution coefficients, vapor pressure, and water solubility). The descriptors are suitable for use in the solvation parameter model and facilitate the estimation of a wide range of physicochemical, chromatographic, biological, and environmental properties using existing models.

• 出版日期2012-10