New protocol for one-pot synthesis of functionalized symmetrical 1,4-dialkyl- or 1,4-diaryl-1,3-diynes

作者：Rzonsowska Monika; Dudziec Beata; Kownacki Ireneusz; Marciniec Bogdan^*

来源：Journal of Organometallic Chemistry, 2015, 775: 20-26.

DOI：10.1016/j.jorganchem.2014.10.015

• Silylative coupling
• Alkynes
• Vinylsilanes
• Ruthenium
• Iridium
• Glaser type coupling

A new versatile one-pot protocol for preparation of functionalized 1,4-disubstituted-1,3-diynes via a highly selective catalytic silylative coupling of vinylsilanes and terminal alkynes occurring via [Ru] catalyzed reaction and/or [Ir] catalyzed reaction of iodosilanes with alkynes followed by desilylative homocoupling sequence is presented. Contrary to existing stoichiometric systems, the catalytic conditions for the copper salt mediated homocoupling of trimethylsilylalkyne were elaborated that are very tolerant to various functional groups.

• 出版日期2015-1-1