MRI in Diagnosis of Orbital Masses

作者：Roshdy Nader; Shahin Maha; Kishk Hanem^*; Ghanem Asaad A; El Khouly Sherif; Mousa Amany; Elsalekh Iman

来源：Current Eye Research, 2010, 35(11): 986-991.

DOI：10.3109/02713683.2010.506966

• Magnetic resonance imaging
• Orbital masses

Purpose: To evaluate the role of diffusion-weighted magnetic resonance imaging and proton magnetic resonance spectroscopy in diagnosis of different orbital masses and their advantages over conventional magnetic resonance imaging.
Methods: The study included 32 patients presenting with proptosis. Every patient was subjected to a clinical examination; conventional MRI "T1 weighted, T2 weighted, and post-contrast T1 weighted if needed;" diffusion-weighted MRI; and proton magnetic resonance spectroscopy. Orbitotomy was performed, the orbital mass was excised, and histopathological examination was performed.
Results: Diffusion-weighted MRI can be used to differentiate between benign lesions and malignant tumors in 75% of cases; however, overlap occurred in 25% of cases with benign tumors showing restricted diffusion while proton magnetic resonance spectroscopy could differentiate between benign and malignant tumors in 93.7% of cases.
Conclusion: Diffusion-weighted MRI and proton magnetic resonance spectroscopy increased the accuracy of diagnosis of orbital masses through giving in vivo tissue characterization; with magnetic resonance spectroscopy being more accurate.

• 出版日期2010-11