Association of neck circumference and cognitive impairment among Chinese elderly

作者：Chen, Jin-Mei; Li, Qing-Wei; Jiang, Guo-Xin; Zeng, Shu-Jun; Shen, Jun; Sun, Ji; Wu, Dan-Hong^*; Cheng, Qi^*

来源：Brain and Behavior, 2018, 8(3): e00937.

DOI：10.1002/brb3.937

• cognitive impairment
• elderly
• interaction
• neck circumference
• risk factor

Objectives: To investigate the association between neck circumference (C) and cognitive impairment and interactions between relevant variables to the risk of cognitive impairment.
Methods: A population-based survey was conducted among elderly inhabitants aged 60 years and over from a community in Shanghai suburb. Multivariate logistic regression analyses were performed to evaluate associations and log likelihood ratio tests to examine interactions.
Results: Cognitive impairment was identified in 269 (10.8%) subjects from 2,500 participants. Higher BMI (OR = 1.55; 95% CI = 1.11-2.16), higher WHR (OR = 1.44; 95% CI = 1.07-1.95), and higher total cholesterol (TC) (OR = 1.52; 95% CI = 1.09-2.13) were significantly associated with the increased risk of cognitive impairment. Significant interactions were observed between TC and a few other relevant variables, respectively.
Conclusions: NC was associated with the high risk of cognitive impairment. Additive effects of NC with TC on cognitive impairment were observed.

• 出版日期2018-3
• 单位上海交通大学; 复旦大学; 同济大学