Balloon pulmonary angioplasty: an additional treatment option to improve the prognosis of patients with chronic thromboembolic pulmonary hypertension

作者：Taniguchi Yu; Miyagawa Kazuya; Nakayama Kazuhiko; Kinutani Hiroto; Shinke Toshiro; Okada Kenji; Okita Yutaka; Hirata Ken ich; Emoto Noriaki^*

来源：Eurointervention, 2014, 10(4): 518-525.

DOI：10.4244/eijv10i4a89

• balloon pulmonary angioplasty
• chronic thromboembolic pulmonary hypertension
• operability
• pulmonary endarterectomy

Aims: To evaluate the efficacy and safety of balloon pulmonary angioplasty (BPA) in patients with non-operable chronic thromboembolic pulmonary hypertension (CTEPH) using the results of pulmonary endarterectomy (PEA) for operable patients as a reference, and annotate the role of BPA in the management of CTEPH.
Methods and results: Data from 53 CTEPH patients were collected retrospectively. Twenty-four operable patients underwent PEA, and 29 non-operable patients underwent BPA. Patients who underwent BPA showed improved mean pulmonary arterial pressure, pulmonary vascular resistance, and cardiac output (39.4 +/- 6.9 to 21.3 +/- 5.6 mmHg, 763 +/- 308 to 284 +/- 128 dyn.s(-1)cm(-5), 3.47 +/- 0.80 to 4.26 +/- 1.15 L/min, respectively); patients who received PEA showed similar efficacy (44.4 +/- 11.0 to 21.6 +/- 6.7 mmHg, 781 +/- 278 to 258 +/- 125 dyn.s(-1).cm(-5), 3.35 +/- 1.11 to 4.44 +/- 1.58 L/min, respectively). The mortality rates of BPA and PEA patients were 3.4% and 8.3%, respectively.
Conclusions: The efficacy and safety of BPA for non-operable cases were similar to those achieved using PEA for operable cases. BPA could be an additional treatment option for non-operable CTEPH patients, and most CTEPH patients can be satisfactorily treated by BPA or PEA.

• 出版日期2014-8