A systematic study of antibacterial silver nanoparticles: efficiency, enhanced permeability, and cytotoxic effects

作者：Azocar Manuel I^*; Tamayo Laura; Vejar Nelson; Gomez Grace; Zhou Xiangrong; Thompsom George; Cerda Enrique; Kogan Marcelo J; Salas Edison; Paez Maritza A

来源：Journal of Nanoparticle Research, 2014, 16(9): 2465.

DOI：10.1007/s11051-014-2465-4

• Silver
• Nanoparticles
• Antibacterial
• Cytotoxicity
• Permeability
• Environmental and health effects

We report here a systematic study of the antibacterial behavior of silver nanoparticles coated with fatty acids (oleic: AgNP-O, linoleic: AgNP-L, and palmitic acids: AgNP-P) in water. We have found remarkable differences in their capability to penetrate bacteria cell over a broader range of particle size of similar to 4-96 nm compared to previously reported work, and a variable toxicity depending on the particles size. Our results indicate that silver nanoparticles stabilized with oleic acid showed clear advantages in antibacterial activity, penetration inside the bacteria cells, cytotoxicity, time effectiveness, efficiency, and stability against light.

• 出版日期2014-8-15