Ambient Ionization-Paper Spray Ionization and Its Application

作者:Zhang Zhi Ping*; Liu Xiao Ning; Zheng Ya Jun
来源:Chinese Journal of Analytical Chemistry, 2014, 42(1): 145-152.
DOI:10.3724/SP.J.1096.2014.30831

摘要

Ambient ionization has gained increasing attentions in recent years due to its characteristics of convenience, high efficiency and without sample pretreatment prior to analysis. Although ambient ionization has gotten the considerable development and has been applied in diverse fields for rapid detection, high. throughput analysis of complex samples has put forward higher requirements to ambient ionization. mass spectrometry. Paper spray ionization source is recently developed with ambient ionization, which has demonstrated promising in high. throughput analysis of foodstuffs and drugs due to its facile operation, low. cost and simple separation in analysis. Herein, the development of paper spray ionization was comprehensively reviewed, and the basic principle, influencing factors, performance of paper spray and its applications were highlights. Also, the advantages and disadvantages of this technique were discussed followed by its development directions.

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