A new perylene bisimide-armed calix[4]-aza-crown as "turn on" fluorescent sensor for Hg2+ ion and its application to living cells

作者：Erdemir Serkan^*; Kocyigit Ozcan; Karakurt Serdar

来源：Sensors and Actuators B: Chemical , 2015, 220: 381-388.

DOI：10.1016/j.snb.2015.05.103

• Perylene
• Calixarene
• Fluorescent
• Turn on
• Mercury

We report the design and synthesis of a new perylene bisimide derivative containing calix[4]arene units (PB-CX[4]) as "turn on" fluorescent sensor for Hg2+ ion determination. PB-CX[4] showed highly selective and sensitive "turn-on" fluorescent responses toward Hg2+ ion based on photoinduced electron transfer (PET) mechanism in DMF/H2O (v/v, 9515). The binding analysis using a Job plot suggested that PB-CX[4] formed a 1:2 complex with He. The association constant (K) of PB-CX[4]-Hg2+ complex was found to be 1.66 x 10(9) M-7, with a detection limit of 5.56 x 10(-7) M. In addition, possible utilization of PB-CX[4] as bio-imaging fluorescent probe to detect Hg2+ in human colon cancer cell lines was also observed by confocal fluorescence microscopy.

• 出版日期2015-12-1