An Efficient Dimethylacetamide-Promoted Conversion of Alcohols to Alkyl Chlorides

作者:Zheng, Dagui*; Zhou, Anxi; Zhu, Xianhong; Zheng, Hongfu; Sun, Xiangqian
来源:Chinese Journal of Organic Chemistry, 2016, 36(1): 137-142.
DOI:10.6023/cjoc201507020

摘要

A simple and efficient method for the conversion of alcohols to the corresponding alkyl chlorides by using dimethylacetamide (DMAc) as a promoter was developed. It provides a new and practical protocol for the synthesis of alkyl chlorides.