Durable response of cutaneous squamous cell carcinoma following high-dose peri-lesional injections of Viscum album extracts - A case report

作者：Werthmann Paul Georg^*; Straeter Gregor; Friesland Hedda; Kienle Gunver Sophia

来源：Phytomedicine, 2013, 20(3-4): 324-327.

DOI：10.1016/j.phymed.2012.11.001

• Mistletoe
• Viscum
• Cutaneous squamous cell carcinoma
• Case report

Background: Cutaneous squamous cell carcinoma (CSCC) is a common locally invasive skin cancer which rarely metastasises. First-line treatment is surgical excision, which is curative in most cases. Viscum album extract (VAE) is a widely used herbal cancer treatment with cytotoxic, apoptogenic and immunological effects, but has not been investigated in CSCC.
Case presentation: A 78-year-old patient with histologically diagnosed CSCC refused surgical excision and was treated with peri-lesional high-dose VAE. After 10 months of treatment the CSCC had disappeared clinically. The patient has been recurrence-free for 4 years.
Conclusion: The presented case shows clinical response of a CSCC to high-dose peri-lesional VAE injections. Further research on VAE in CSCC is warranted.

• 出版日期2013-2-15