Resistance to inhibitors of the human immunodeficiency virus type 1 integration

作者：Hazuda Daria J^*

来源：Brazilian Journal of Infectious Diseases, 2010, 14(5): 513-518.

DOI：10.1590/S1413-86702010000500016

• antiretrovirals
• integrase inhibitors
• raltegravir

This review will summarize the role of integrase in HIV-1 infection, the mechanism of integrase inhibitors and resistance with an emphasis on raltegravir (RAL), the first integrase inhibitor licensed to treat HIV-1 infection.

• 出版日期2010-10