A simple and convenient synthesis of 2-methoxyestradiol from estrone

作者：Prakasham A P; Shanker Karuna; Negi Arvind S^*

来源：Steroids, 2012, 77(5): 467-470.

DOI：10.1016/j.steroids.2012.01.005

• 2-Methoxyestradiol
• Breast cancer
• Total synthesis

A simple and straightforward synthesis of 2-methoxyestradiol have been achieved in nine synthetic steps with 21% of overall yield. Being a convenient process, it can be upscaled to industrial process.

• 出版日期2012-4
• 单位河北医科大学