Emerging Electrical Biosensors for Detecting Pathogens and Antimicrobial Susceptibility Tests

作者：Yen Pei Wen; Lu Yen Pei; Lin Chih Ting; Hwang Chi Hung; Yeh J Andrew; Lin Ming Yu^*; Huang Keng Shiang

来源：Current Organic Chemistry, 2014, 18(2): 165-172.

DOI：10.2174/13852728113176660140

• Pathogens
• Electrical biosensors
• Human immunodeficiency virus (HIV)
• Tuberculosis (TB)
• group B Streptococcus (GBS)
• methicillin-resistant Staphylococcus aureus (MRSA)

The past decade has witnessed the development of innovative biosensing technologies for detecting pathogens, and evaluating the anti-microbial susceptibility test in the infectious diseases. Recent advances in the field have been focused on the development of miniaturized biosensors with high sensitivity, specificity and stability. Possibility for commercialization is also a key criterion to develop biosensors in reality. In this article, we introduced several electrical-based biosensors with prospective for commercialization. To have an in-field detection for pathogens, the electrical biosensor is promising because of its ease to be implemented with micro/nano fabrication technologies. Several electrical biosensing techniques, such as ion-sensitive field effect transistor, nanowire, and microcantilever have been introduced. In addition, advantages and achievements of each electrical biosensing technique have also been reviewed.

• 出版日期2014-1
• 单位清华大学