A 5-year report from a multicentre randomised clinical trial: immediate non-occlusal versus early loading of dental implants in partially edentulous patients

作者：Capelli Matteo; Esposito Marco^*; Zuffetti Francesco; Galli Fabio; Del Fabbro Massimo; Testori Tiziano

来源：European Journal of Oral Implantology, 2010, 3(3): 209-219.

• dental implants
• early loading
• follow up
• immediate loading
• partial edentulism

Purpose To compare pen-implant bone and soft-tissue levels of immediately non-occlusally loaded versus non submerged early loaded implants in partially edentulous patients 5 years after implant placement
Materials and methods Fifty-two patients were randomised in five Italian private practices 25 in the immediately loaded group and 27 in the early loaded group To be immediately loaded, single implants had to be inserted with a torque of > 30 Ncm, and splinted implants with a torque of > 20 Ncm Immediately loaded implants were provided with non-occluding temporary restorations within 48 hours After 2 months, the provisional restorations were put in full occlusion Implants were early loaded after 2 months Final restorations were provided 8 months after implant place ment Outcome measures were prosthesis and implant failures as well as biological and prosthetic complications recorded by non-blinded assessors Blinded assessors evaluated pen-implant bone and soft-tissue levels
Results Fifty-two implants were immediately loaded and 52 early loaded One patient of the early loaded group dropped out after the 1-year recall One single immediately loaded implant failed 2 months after placement Only one complication (iatrogenic pen-implantitis) occurred in one patient of the early loading group Both groups gradually lost pen-implant bone in a highly statistically significant way at 2, 8 and 14 months and at 4 and 5 years After 5 years, patients of both groups had lost an average of 1 2 mm of pen-implant marginal bone There were no statistically significant differences in pen-implant bone and soft-tissue level changes between the 2 groups At 5 years, there was a statistically significant recession (0 2 mm) of the vestibular soft tissues from baseline (delivery of the final restorations 8 months after implant placement) only for immediately loaded implants
Conclusions In well maintained patients, complications are uncommon and healthy and stable penimplant tissues can be maintained for 5 years around immediately and early loaded implants

• 出版日期2010