Associations among gender, marital status, and outcomes of adult in-hospital cardiac arrest: A retrospective cohort study

作者：Wang Chih Hung; Huang Chien Hua; Chang Wei Tien; Tsai Min Shan; Yu Ping Hsun; Wu Yen Wen; Chen Wen Jone^*

来源：Resuscitation, 2016, 107: 1-6.

DOI：10.1016/j.resuscitation.2016.07.005

• Heart arrest
• Cardiopulmonary resuscitation
• Critical care
• Gender
• Marriage

Aim: To analyse the association between gender and outcomes of in-hospital cardiac arrest (IHCA) and the influences of age and marital status on the gender-based difference in clinical outcome.
Methods: This retrospective observational study conducted in a single medical centre evaluated patients who had experienced IHCA from 2006 to 2014. Multivariate logistic regression analysis was used to study associations between independent variables and outcomes. Patients 18-49 years old were considered of reproductive age. The presence or absence of a legitimate spouse was retrieved from the family pedigree presented in the medical records. Reproductive age and marital status were each analysed as an interaction term with gender.
Results: A total of 1524 patients, of which 598 were women (39.2%), were included in this study. There were 269 patients (17.7%) of reproductive age and 490 patients (32.2%) without a living spouse. Only 215 patients (14.1%) survived to hospital discharge. Among these, 110 patients (7.2%) demonstrated a favourable neurological status. Our analysis indicated that being female was inversely associated with a favourable neurological outcome (odds ratio [OR], 0.51; 95% confidence interval [CI], 0.29-0.87; p = 0.02). Being female without a living spouse was inversely associated with a favourable neurological outcome (OR, 0.43; 95% CI, 0.17-0.96; p = 0.05). Neither female nor female-associated interaction terms were significantly associated with survival to hospital discharge.
Conclusion: Female patients with IHCA had worse neurological outcomes than their male counterparts, especially for women without a living spouse. However, survival outcome did not differ between genders.

• 出版日期2016-10