Association between vitamin D status and metabolic syndrome risk among Korean population: Based on the Korean National Health and Nutrition Examination Survey IV-2, 2008

作者：Kim Soyeun; Lim Juwon; Kye Soshin; Joung Hyojee^*

来源：Diabetes Research and Clinical Practice, 2012, 96(2): 230-236.

DOI：10.1016/j.diabres.2012.01.001

• Vitamin D deficiency
• 25(OH)D
• KNHANES
• Metabolic syndrome

Aims: Low serum 25-hydroxyvitamin D (25(OH)D) levels have been linked to metabolic syndrome. However, community-based data for healthy Korean individuals are lacking. We aimed to assess the vitamin D status and the association of 25(OH)D deficiency with metabolic syndrome in the South Korean population (latitude 33-38 degrees N).
Methods: In this population-based study, we assessed 5559 South Korean adults selected from the Korean National Health and Nutrition Examination Survey IV-2, 2008. We used multiple logistic regression analysis to assess the association between vitamin D deficiency and metabolic syndrome.
Results: The prevalence of vitamin D deficiency (<20 ng/mL) was 56.0%. Subjects with vitamin D deficiency were younger and had higher education, lower physical activity, and lower alcohol consumption than those with normal vitamin D levels. The overall risk of metabolic syndrome was not associated with 25(OH)D concentration. The adjusted OR of reduced high density lipoprotein cholesterol (HDL-C) decreased across the quintiles of 25(OH)D concentrations (OR = 0.72; 95% confidence interval = 0.54-0.95 for comparisons of lowest vs. highest quintile; P for trend = 0.003).
Conclusions: A high prevalence of vitamin D deficiency was noted in the general South Korean population. Serum 25(OH)D concentration was inversely associated with the risk of having reduced HDL-C.

• 出版日期2012-5