Different Chromatographic and Electrophoretic Methods for Analysis of Proton Pump Inhibitors (PPIs): A Review

作者：El Kommos Michael E; Khashaba Pakinaz Y; Ali Hassan Refat H; El Wekil Mohamed M^*

来源：Journal of Liquid Chromatography & Related Technologies, 2015, 38(18): 1639-1659.

DOI：10.1080/10826076.2015.1079722

• biological analysis
• chromatographic methods
• combined mixtures
• electrophoretic methods
• pharmaceutical analysis
• proton pump inhibitors

A systematic comprehensive review of literature for the analysis of the most recent antiulcer drugs and proton pump inhibitors (PPIs) by different chromatographic and electrophoretic methods are presented. The review includes literature from 1985 until 2015 on eight proton pump inhibitors; namely: omeprazole (OMZ), lansoprazole (LAN), pantoprazole (PAN), rabeprazole (RAB), esomeprazole (EMZ), dexlansoprazole (DLAN), dexrabeprazole (DRAB), and tenatoprazole (TNB). The investigated literature survey covers most chromatographic and electrophoretic methods used for the assay of these drugs in pure forms, in combined mixtures, in pharmaceutical dosage forms, and in biological fluids.

• 出版日期2015-11-8