Aging gonads, glands, and gametes: immutable or partially reversible changes?

作者：Meldrum David R^*

来源：Fertility and Sterility, 2013, 99(1): 1-4.

DOI：10.1016/j.fertnstert.2012.10.044

• Reproductive aging
• oxidative stress
• lifestyle
• supplements

Decreased ovarian testosterone production, granulosa cell dysfunction, oocyte telomere shortening and mitochondrial defects, and sperm DNA fragmentation all contribute to reproductive aging. Maneuvers aimed at correcting these abnormalities, including reduction of oxidative stress, improved lifestyle and nutrition, and the role of supplements, are reviewed. (Fertil Steril (R) 2013;99:1-4.

• 出版日期2013-1