Diastereoselective Synthesis of Substituted Tetrahydrothiophenes and -thiopyrans via Thia-Prins Cyclization Reaction

作者:Borah Madhurjya; Gogoi Paramartha; Indukuri Kiran; Saikia Anil K*
来源:Journal of Organic Chemistry, 2015, 80(5): 2641-2648.
DOI:10.1021/jo502831w

摘要

Tetrahydrothiophenes and -thiopyrans have been efficiently synthesized from thioacrylates via thia-Prins cyclization reaction mediated by trimethylsilyltrifluoromethanesulfonate with good diastereoselectivity and in good to high yields.

  • 出版日期2015-3-6