Asymmetric Synthesis of the C(7)-C(23) Fragment of Iriomoteolide-1a

作者：Xie Jun; Ma Yuelong; Horne David A^*

来源：Organic Letters, 2009, 11(21): 5082-5084.

DOI：10.1021/ol902110a

An efficient synthesis of the C(7)-C(23) fragment 2 of iriomoteolide-1a (1) has been accomplished via a B-alkyl Suzuki-Miyaura cross-coupling reaction followed by deprotection and cyclization to form the cyclic hemiketal core.

• 出版日期2009-11-5