科研之友
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摘要
This Study describes the symmetric synthesis of novel beta-lactams derived from chrysene directed towards their SAR, as well as their biological activities against several cancer cell lines in vitro. To our knowledge, this is the first report oil the synthesis and biological evaluation of optically active anticancer beta-lactams. That these anticancer effects are not uniform against all tumor lines suggests that the target of the action of these compounds is highly specific.
- 出版日期2010-4
