Direct olefination of benzaldehydes into 1,3-diarylpropenes via a copper-catalyzed heterodomino Knoevenagel- decarboxylation-Csp(3)-H activation sequence

作者：Zhao, Yaping; Sun, Lu; Zeng, Tieqiang; Wang, Jiayi; Peng, Yanqing; Song, Gonghua^*

来源：Organic and Biomolecular Chemistry, 2014, 12(21): 3493-3498.

DOI：10.1039/c4ob00155a

• CROSS-COUPLING REACTIONS
• BETA-LACTAM RESISTANCE
• (-)-EPICATECHIN GALLATE
• ARYLBORONIC ACIDS
• ORGANIC-SYNTHESIS
• DOMINO REACTIONS
• ANALOGS
• DERIVATIVES
• ALCOHOLS
• INHIBITORS

Copper-catalyzed direct olefination of benzaldehydes into 1,3-diarylpropenes by a novel domino Knoevenagel-decarboxylation-Csp(3)-H activation sequence is reported. This method provides a concise and effective route toward the synthesis of unsymmetrical 1,3-diarylpropene derivatives.

• 出版日期2014
• 单位华东理工大学