Do Current Animal Models of Intracerebral Hemorrhage Mirror the Human Pathology?

作者:Adeoye Opeolu*; Clark Joseph F; Khatri Pooja; Wagner Kenneth R; Zuccarello Mario; Pyne Geithman Gail J
来源:Translational Stroke Research, 2011, 2(1): 17-25.
DOI:10.1007/s12975-010-0037-1

摘要

Although intracerebral hemorrhage (ICH) has no proven treatment, well-designed studies using animal models of ICH may lead to the development of novel therapies. We briefly review current animal models of ICH. Furthermore, we discuss how these models may be utilized and targeted to facilitate translation of preclinical findings to the clinical arena.

  • 出版日期2011-3