Acute Dystonia Following a Switch in Treatment from Atomoxetine to Low-dose Aripiprazole

作者:Basay Omer; Basay Burge Kabukcu*; Ozturk Onder; Yuncu Zeki
来源:Clinical Psychopharmacology and Neuroscience, 2016, 14(2): 221-225.
DOI:10.9758/cpn.2016.14.2.221

摘要

The present report describes the cases of a 17 year old male patient and a 13 year old female patient who developed acute dystonia following the administration of low dose aripiprazole (5 mg/day) after the cessation of atomoxetine treatment. Although aripiprazole induced dystonia has been previously reported in the literature, it is rare, and most of these cases were associated with doses higher than 5 mg/day. Furthermore, both of the patients in the present study discontinued atomoxetine prior to the initiation of aripiprazole treatment; thus, this report also discussed the possible mechanisms underlying the manifestation of dystonia from the perspective of neurotransmitter activity.

  • 出版日期2016-5