Multiple cavitary pulmonary nodules in association with pyoderma gangrenosum - Case report

作者：Semblano Bittencourt Maraya de Jesus; Brito Soares Luciana Fontenele; Lobato Lilia Sampaio; Mancano Alexandre Dias; Castro Leandro Helandro Stuart

来源：Anais Brasileiros de Dermatologia, 2012, 87(2): 301-304.

• Cavitation
• Multiple pulmonary nodules
• Pyoderma gangrenosum
• Wegener granulomatosis

Pyoderma gangrenosum is a rare neutrophilic disease of unknown origin that is associated with systemic diseases in 50% of cases. It is characterized by erythematous-violaceous nodular lesions that quickly progress to painful ulcers, with undermined edges, necrotic-hemorrhagic, varying in size and depth, located mainly in the lower limbs. Extracutaneous locations of pyoderma gangrenosum are rare, usually involving the lungs; the main differential diagnosis in these cases is Wegener granulomatosis. We report a case of pyoderma gangrenosum, which showed multiple cavitary lung nodules, with good response to high doses of steroids. Once excluded the possibility of Wegener granulomatosis, the authors concluded that it was the manifestation of systemic pyoderma gangrenosum with pulmonary involvement.

• 出版日期2012-4