Neural network imaging to characterize brain injury in cardiac procedures: the emerging utility of connectomics

作者：Indja B; Fanning J P; Maller J J; Fraser J F; Bannon P G; Vallely M; Grieve S M^*

来源：British Journal of Anaesthesia, 2017, 118(5): 680-688.

DOI：10.1093/bja/aex088

• cardiac surgical procedures
• connectome
• coronary artery bypass
• off-pump
• neuroimaging
• postoperative complications

Cognitive dysfunction is a poorly understood but potentially devastating complication of cardiac surgery. Clinically meaningful assessment of cognitive changes after surgery is problematic because of the absence of a means to obtain reproducible, objective, and quantitative measures of the neural disturbances that cause altered brain function. By using both structural and functional connectivity magnetic resonance imaging data to construct a map of the inter-regional connections within the brain, connectomics has the potential to increase the specificity and sensitivity of perioperative neurological assessment, permitting rational individualized assessment and improvement of surgical techniques.

• 出版日期2017-5