A molecularly imprinted polymer for the selective solid-phase extraction of dimethomorph from ginseng samples

作者：Xu, Xuanwei^*; Liang, Shuang; Meng, Xinxin; Zhang, Min; Chen, Ying; Zhao, Dan; Li, Yueru

来源：Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences, 2015, 988: 182-186.

DOI：10.1016/j.jchromb.2015.02.033

• Molecularly imprinted polymers
• Dimethomorph
• Precipitation polymerization
• Solid-phase extraction
• Ginseng samples

A molecularly imprinted polymer (MIP) was synthesized and evaluated to selectively extract dimethomorph from ginseng samples. Dimethomorph molecularly imprinted polymers with template to monomer molar ratios were contrived and developed via precipitation polymerization employing methacrylic acid as functional monomer, ethylene dimethacrylate as cross-linker and butanone:N-heptane (7:3, v:v)as porogen. The LOD (limit of detection) of this method was 0.002 mg kg(-1), and the LOQ (limit of quantification) was 0.005 mg kg(-1). The different spiked level of ginseng was 0.1 mg kg(-1), 1.0 mg kg(-1), 5.0 mg kg(-1), and the average recovery of dimethomrph was 89.2-91.6%. Under the optimized condition, good linearity was obtained from 0.01 to 5 mg kg(-1) (r(2) > 0.9997) with the relative standard deviations of less than 3.20%. This proposed MISPE-GC procedure eliminated the effect of template leakage on quantitative analysis and could be applied to direct determination of dimethomrph in ginseng samples.

• 出版日期2015-4-15
• 单位吉林农业大学