Annulation of Benzamides with [60]Fullerene through Palladium(II)-Catalyzed C-H Bond Activation

作者：Chuang Shih Ching^*; Rajeshkumar Venkatachalam; Cheng Chun An; Deng Jie Cheng; Wang Guan Wu

来源：Journal of Organic Chemistry, 2011, 76(6): 1599-1604.

DOI：10.1021/jo102107k

Palladium-catalyzed heteroannulation of N-substituted benzamides with [60]fullerene, which proceeds through direct sp(2) C-H bond activation to form 7-membered ring pallada-intermediate with C-60, led to formation of [60]fulleroisoquinolinones in moderate to good yields (8-64% based on recovered C-60). A plausible reaction pathway is proposed.

• 出版日期2011-3-18
• 单位中国科学技术大学